About Us

Research group.

The Atlas of Curated Splicing Regulators in Humans (IARA) is an initiative of the research group led by Professor Roberto Hirochi Herai, Researcher of the Postgraduate Program in Health Sciences, at the School of Medicine of the Pontifical Catholic University of Paraná/PUCPR (Curitiba, Brazil).

The IARA was created due to the need to gather information about which factors are involved in the process of regulating the splicing mechanism in human, with a view to obtaining cured and updated data.

Publications

If you use Atlas of Curated Splicing Regulators in Humans in your work, please cite the following manuscript:

Rodrigues KS, Petroski LP, Utumi PH, Ferrasa A, Herai RH. IARA: a complete and curated atlas of the biogenesis of spliceosome machinery during RNA splicing. Life Sci Alliance. 2023 Jan 6;6(3):e202201593. doi: 10.26508/lsa.202201593. PMID: 36609432; PMCID: PMC9834665.

The main researchers involved are:


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HERAI, R. H.

Postdoctoral in Pediatrics/Molecular and Cellular Medicine (University of California San Diego, USA). Dr. Herai works in the field of genetics and bioinformatics, with an emphasis on genetic investigation of autism spectrum disorders, metabolic networks, systems biology, analysis and interpretation of genetic data related to large-scale genetic sequencing technologies and genetic editing using technique CRISPR.


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RODRIGUES, K. S.

Biotechnology undergraduate of the Pontifical Catholic University of Paraná/PUCPR (Curitiba, Brazil) and Scientific Initiation student, focusing on the detection of alternative splicing isoforms in transcriptome RNA-seq sequencing data derived from MeCP2 protein knockout neurons.


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PETROSKI, L. P.

Doctoral candidate in Bioinformatics at the Pontifícia Universidade Católica do Paraná. / PUCPR (Curitiba, Brazil). He has a degree in Computer Engineering and a Masters in Applied Computing. He works in the field of bioinformatics applying artificial intelligence techniques for analyzing and interpreting genetic data.


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UTUMI, P. H.

Doctoral candidate in Bioinformatics at the Pontifícia Universidade Católica do Paraná. / PUCPR (Curitiba, Brazil). Graduated in Biology from Pontifical Catholic University of Paraná (2012) performing scientific initiation during the period in ​​physiology. Has master's degree in Animal Science from Pontifical Catholic University of Paraná (2019) where he carried out the characterization of stem cells derived from dental pulp and umbilical cord of dogs. He is currently a doctoral student in postgraduate program in health sciences in bioinformatics with a research project on Alternative Splicing in Rett Syndrome.


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FERRASA, A.